Space-time block coding (STBC) is a novel transmit diversity technique that can substantially improve the reliability of wireless communication channel. In this letter, we investigate single-carrier STBC block transmission over frequency-selective fading channel. Based on the minimum mean square error (MMSE) criterion, by exploiting the reliability of tentative decision symbols, we propose a novel suboptimal, low complexity frequency domain decision feedback equalization (FD-DFE) scheme for SC STBC. Simulation results show that the proposed scheme provides better performance than the conventional scheme.