The laser-induced damage experiments are finished under the conditions that Q-switched Nd glass laser (the output pulse amplitude is 8.7ns, wavelength are times of 1053nm, 527nm, 351nm) effects on the undoped glass-metal ions M0 and the incorporation of metal ions glass M1, M2. The test results show that: with the irradiation of the fundamental laser, the laser-induced damage threshold of M1 is reduced by 23% than M0; with the irradiation of second harmonic light, the laser-induced damage threshold of M2 is reduced by 23% than M0; with the irradiation f third harmonic radiation, the damage threshold of all glass is basically the same. Observed laser-induced damage of glass under optical microscope with fluorescence, we find that only M1 at the fundamental frequency of the laser light irradiation and M2 in the second harmonic of the laser light irradiation have visible damage central damage and crack. Through the analysis we know that the metal ion absorb laser radiation is the direct reason of surface damage reduce of laser damage threshold of glass.