A low-power high data rate optical packet switch integrating hybrid silicon Mach-Zehnder Interfer-ometer (MZI) based optical switch and 0.13µm CMOS IC for data center switching application is described. A novel truly differential transimpedance amplifier (TIA), with high-bandwidth power supply rejection ratio (PSRR), that serves as the front-end for a 2Gbps packet-header receiver is presented. The TIA achieves 55.7dB and 1.97GHz f3dB while consuming 3.3mW from 1.2V supply excluding 50Ω output driver. We also demonstrate a low-power optical switch driver enabled by a compact supply-regulated driver that features variable output voltage and power-boost for fast rise times. The CMOS driver chip is wirebonded to photonic IC, achieving≤5ns switching time while consuming 250µW.