In hybrid automatic repeat request (HARQ), maximum ratio combining (MRC) is usually employed at the receiver if the retransmission signal is the same as that in the first transmission. However, conventional performance analysis of HARQ and MRC does not consider that all previous transmissions fail. In this paper, we analyze the conditional error rate of HARQ with arbitrary combining schemes. Both the theoretical and approximate expressions of the conditional error rate are derived. Our analytical and simulation results reveal that conventional MRC is not optimum for HARQ, especially when the packet is short or the channel gain of the first transmission is much better than that of retransmission.