Miniaturized atomic clock could provide the most stable frequency reference. Atomic Vapor Cell is the most important component for atomic clock. A method based on vacuum packaging to conduct the glass-silicon-glass anodic bonding using two electrodes for atomic vapor cell fabrication was developed. Based on the method of laser drilling and surface analysis, a novel process for atomic vapor cell fabrication with cavity by laser drilling was proposed. Tensile strength test shows that the samples could obtain 9MPa ∼ 10MPa. The spectrum analysis demonstrated the alkali metal was well sealed.