“GNU Radio Beacon Receiver (GRBR) is a new digital receiver based on GNU Radio and USRP (Universal Software Radio Peripheral) [Yamamoto, 2008]. In this paper, the GRBR observations of large-scale wave structure (LSWS) and the subsequent development of equatorial spread F (ESF) using total electron content (TEC) derived from the ground based reception of signals from the radio beacon on board C/NOFS (Communications/Navigation Outage Forecasting System) satellite are presented. The other evidences of LSWS include the ‘satellite traces’ observed in ionograms. These observations show that LSWS appears to play an important role in the development of ESF.