The human resources is playing a daily important role in modern globalized firms. Appropriate staffing strategies are critical for coordinating and controlling international human resource management related issues across widely distributed business units or subsidiaries over various geographic areas. However, very few researches tried to uncover how the expatriate managers can be selected, especially when the evaluation criteria influence each other. Thus, this research aims to develop a decision framework for selecting appropriate expatriate managers. A multiple criteria decision making (MCDM) framework consisting of the Decision Making Trial and Evaluation Laboratory (DEMATEL) for structuring the decision problem, the Analytical Network Process (ANP) for deriving weights versus each criterion, and finally, the VlseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR) for ranking the alternatives have been proposed. An empirical study based on a globalized high technology firm will be leveraged for verifying the usefulness of this proposed analytic framework on staff selections.