Set USB to CAN single point of communication protocol, developed LabVIEW-based engine calibration system easy to complete the calibration system software development and design, in the experiment, the system can be a good start, run, stop, and accurate implementation of the operation and Display information in real time to control the engine, the engine status changed, but also pre-set by the experimenter read the data accurately and precisely the engine real-time data were stored to the computer.