The monitoring about the changes of land use and cover and NPP in mining area is one of hot spots in the field of resources and environment. Combining with ground field survey data, the remote sensing image in different periods in mining area and the geographic information technology are used to study the changes of Land Use and Cover and NPP. The results show that the degree of the change of land use and cove from 2000 to 2010 is higher than the degree from 1990 to 2000. The types of land use and cover also change more violent. The land utilization degree is increasing. It shows that human activities have bigger interference to the districts. The NPP in 2010 is more than the NPP in 2000 and it is lower than the NPP in 1990.