The industry's most accurate 2.5 V bandgap voltage reference is presented with true 16-bit performance: 1 ppm/C temperature coefficient, 100 μV initial accuracy, 1 μV/V line regulation and 15 μV/mA load regulation. This unique accuracy has been achieved by controlling every important parameter with a dedicated feedback loop, using unconditionally stable single-stage amplifiers. A two-temperature trimming procedure, used on packaged parts at the final test, allows to set the reference value at normal temperature and to remove the first-order temperature drift without the need to store a package ID number. Vbe curvature compensation is implemented with a new, enhanced second-order Taylor approximation. The combination of the mentioned techniques results in a unique implementation of a bandgap reference suitable for any system-on-chip design because it is small in chip area, easily manufacturable, and easy to use, and at the same time shows best in class accuracy.