In this paper, based on the actual design of gear during the production process as well as the gradual formation of gear meshing gear principle and the principle of the establishment of a non-circle gear tooth profile curve of the mathematical model parameters. And then combined with MATLAB and Pro / E to achieve the whole parameters design of the gear, First of all in the MATLAB programming environment compile the program of the curve and to generate consistent with the Pro / E format. IBL document further into Pro / E which achieves gear three-dimensional parametric modeling. In order to achieve the design of gear is shorter and more precise.