Urban Comprehensive Passenger Transportation Hubs (UCPTH) as highly-concentrated passenger distribution sites, the departure time of connection public Transportation exerts great influence on average residence time of passengers who arrive at hubs. Coordination of transfer between the arrival time of passengers carried from outside to hubs and the departure time of various connection public Transportation lines not only facilitates the rapid evacuation of passenger flow, reducing the waiting time of passengers to a maximum, but also can enhance the appeal of connection public Transportation, realize intelligent transportation management and relieve congestion in hubs. For these purposes, optimized model of departure time by means of connection public Transportation in Urban Comprehensive Passenger Transportation Hubs is set up, demonstrating with model algorithm and examples.