Long-span continuous rigid bridge is sensitive to wind actions on largest double cantilever stage before closure. In order to analyze the performance of anti-wind during Rongjiang super bridge construction, worst-case analysis of wind-induced response for several wind loads including various wind directions and attack angles have been performed using random simulation method in time domain. Based on the worst-case analysis, some measures for increasing its performance of anti-wind are discussed due to non-symmetric wind loads. The results indicate that the wind loads with +15° wind direction and +6° attack angle is the worst-case on largest double cantilever stage. In addition, the brace strut can increase the performance of anti-wind effectively, which would be a logical advice during bridge construction.