Throughout the human history that dates back to millions of years the footprints are abundant to illustrate that living with technologies have continuously induced major impacts on the human, social, and organizational transformations. The attributes of human living today and the manner in which the modern societies and organizations are formed indicate a remarkable difference in comparison to the early days of civilizations. As much as modern living becomes very much technology driven and ICT based, it also contributes actively to make it more complex, connected, and exposed. This brings completely new set of dimensions to shape up the future of humans, societies, and organizations. With reference to years of observations and experiences on the aggressive and rapid technological & ICT-based developments, this paper brings the future of human, social, and organizational issues into perspective. It also elaborates on the critical features of the transformations that are conditioned by the attributes of living with modern and emerging technologies.