In this paper, a mathematical model is proposed to estimate the distortion caused by random packet losses for multi-view video transmission. Based on the study of multi-view video coding, the proposed model takes into account the disparity/motion compensation which relates the channel-induced distortion in the current frame with that in the previous frame or the adjacent view, and allows for any motion-compensated and disparity-compensated concealment method at the decoder. Comparative studies between the modeled and simulated distortion results demonstrates that the proposed model is able to estimate the transmission distortion of multi-view video with high accuracy.