Computational Quantitative Biology applications like Genomics, Transcriptomics, Proteomics, Metabolomics and Systems Biology at large require high computing resources that include both processing and storage. Cloud computing provides dynamically scalable on-demand infrastructure in a virtualised environment for processor intensive and data/storage intensive applications. Users need not own this infrastructure; rather use them as and when needed by paying for these resources in pay-as-you-use model that are generally available as a service over the internet. In this paper we present Phoenix - a middleware system for platform as a service (PaaS). This paper describes Phoenix as a novel system for implementing GenomicsCloud - A Cloud computing solution designed specifically to solve OMIC sciences problems. It comprises of a vast pool of compute, storage and application infrastructure for processing the data generated by next generation sequencers (NGS).