A vibration signal analysis system introduced by this paper adopts hybrid programming of Matlab and Delphi, using data file for agency to achieve data communication. The procedure of signal analysis system is written and turned into the independent executable file under the environment of Matlab, which is called under the environment of Delphi. The system combined programming languages of matlab and delphi with comprehensive utilization of powerful numerical calculation processing function of matlab and system exploitation capability of Delphi, which shortens the period of developing system software greatly, saves development costs of exploitation and fully embodies the advantages of the system.