In this paper one will develop the faults detection and localization method using residual vectors, in order to emphasize the noises, disturbances and faults on the outputs L1 and L2 of the control level plant with two coupled tanks ”Quanser Water Level Control Two Tank Module”. The proposed method was theoretically developed and experimentally verified in this plant and allowed detection and localization of two faults created in a real plant. The experiments presented were realized using Matlab Simulink program.