The conceptual hydrogeological model of the study area is generalized according to the hydrogeological conditions, and then the numerical model of groundwater flow is built by MODFLOW-2000. Under current condition of groundwater exploitation, the groundwater flow field in the year 2018 of the study area is forecasted. The result shows the groundwater level will decrease in the river valley of Jixi City, and drainage of local aquifer occurs in the lower reach of Muling River Valley. The numerical model provides a significant scientific basis for sustainable utilization of groundwater resources in Jixi City.