Research concerning innovation management by definition involves multilevel analysis. Focusing on the innovation at individual and organizational levels, this study examines the intensity of the relationship between individual creativity and organizational innovation to identify the construct of innovation composition process across these two levels. Due to a shift in organizational change management, which exceeds the convenience of advanced information technologies (IT), this study identifies and analyzes the effect of virtual organizational (VO) structure on the interaction between individual creativity and organizational innovation. Through the regression analysis of 128 information and electronic companies in Taiwan, the results show that the adoption of VO positively influences organizational innovation. Furthermore, it positively moderates the relationship between individual creativity and organizational innovation.