The paper deals with the following topics: digital simulation; grid computing; production systems; neural networks; artificial intelligence; soft computing; discrete-event systems; genetic algorithms; operations research; bioinformatics; image processing; speech processing; signal processing; knowledge management, enterprise resource planning; social science; economic science; engineering applications; power system application; transportation application; virtual reality; data visualization; computer games; parallel architectures; distributed architectures; Internet; ontologies; electronic engineering applications; e-science; and e-systems.