The growth and competitiveness of new ventures are highlighted and focused on recently. Ctrip, one of fastest-growing companies in the world, exhibits an energetic competitiveness in new ventures. The Strengths, Weakness, Opportunities and Threats (SWOT) analysis model is applied to explore the essential reason of Ctrip's success. It demonstrates that the disruptive innovation is the key factor of Ctrip's success. The importance of the disruptive innovation in new venture is illustrated clearly. If a new venture wants to succeed by the disruptive innovation, it is necessary to recognise a good opportunity to open up a new market, make full use of the capital markets and venture investment to achieve a positive development and gain the market share, and at its initial growth stage, it should sustain disruptive innovation to obtain a good performance. This path of Ctrip's disruptive innovation could be learned by many new ventures.