Based on space-borne multiple-input single-output radar systems, a novel orthogonal bi-phase coding waveform optimization design method is presented. However, it is impossible to design a set of codes with ideal impulsive autocorrelation and idea zero cross-correlation performances. Hence, only the shape of its main-lobe and side-lobe near the detected range cell is considered as the optimization criteria. The aperiodic correlation properties are discussed. Simulation results show that the proposed algorithm is effective and feasible.