The pipeline is taken as the main form of oil transport, and its network has been all over the country. At the current, for the increasing tensions in the oil and gas, the design of pipeline security monitoring system becomes more and more significant. This paper presents a pipeline security online monitoring system based on the ADSP-BF533 and MSP430F149, and gives the design scheme, the main hardware circuits and the main program flow. Experiments show that the system can effectively carry out an early warning to the sabotage of pipelines.