Lack of personalized learning is the key shortcoming of traditional e-learning system. This paper analyzes the personal characters in e-learning activity and presents an innovative design of e-learning system to fully support these personal characters. This new system is user-centric and provides interactive actions with user based on user's learning archive information. This design solution employs multi-layer architecture based on Web including presentation layer, service layer and resource layer. The service layer is divided into business service layer and common service layer that improve the software reusability. It provides the individuation information filtration function which makes the system more intelligent and personalized. The software architecture is implemented in a real system using Struts + Spring + Hibernate framework which is cross-operating system, cross-database, and cross-application server.