Employing analytic hierarchy process (AHP) method, aim to evaluate the effects of wood-based materials on human psychology, physiology, and environment pollution, this article firstly constructed the hierarchical model and endowed the evaluation indexes with corresponding weight value. Furthermore, it scored 20 kinds of wood-based materials and 7 kinds of contrast materials, and then could rank them by their comprehensive scores. The results showed that solid woods have excellent effects on human physiological comfort and psychological satisfaction, while poor contribution to environment pollution. The score of each kind of material has certain positive correlations in the criteria-vector combinatorial space. Based on the differences of comprehensive score, materials can be classified by quality and applicable field into 5 categories.