Sound synthesis employed in many multimedia systems is a useful method to generate sounds of musical instruments. In this paper, we propose a new VLSI architecture suitable for a scalable sound synthesizer based on a programmable data-flow. The sound quality and the level of polyphony can be enhanced only by increasing operating speed and enlarging memory. A fully integrated sound synthesis system is implemented as a prototype to verify the proposed architecture. The prototype chip fabricated in a 0.18-mum CMOS process occupies 1.5 times 1.5 mm2, and can synthesize up to 64-polyphonic sound. The power consumption ranges from 2.05 mW to 13.8 mW depending on the quality of the synthesized sound.