Nowadays,the society makes great demand on E-commerce talents, companies urgently lack the E-commerce professionals who is able to be responsible for the decision-maker, the talents who know both the technology and the E-commerce is quite rare. With the development of Electronic-commerce and the informationization of enterprises management, the content and the method of Electronic-commerce education have changed deeply. So as to do well in talents educating, this paper will make researches on optimizing the E-commerce curriculum system and develops a E-commerce curriculum system based on static & dynamic training mode. This curriculum system centers on the principles of information management, takes computer science and remote telecommunication technology as due instruments and tools in management of information system of the course, and considers knowledge of management science and economics as thinking and methods in designing information management system of the course, the three of which should complement each other. At the same time, in order to improve teaching achievement, this article points out some optimizing measures which should be taken during the teaching process of the compulsory profession course.