In the present paper, we propose the use of enterprise input-output (EIO) models to describe and analyse the logistics flows considering spatial and environmental effects associated with production processes. In particular, transportation is modelled as a specific production process, both at an aggregate and disaggregate level, then permitting to cope with more managerial or policy oriented problems. Moreover, the use of EIO models can be useful to represent and analyse logistics services markets, accounting and planning the demand and supply of transportation.