The terminal design of a data acquisition system based on GPRS is designed in this paper. It works out the hardware design of GPRS terminal equipment, including the minimum system design based on the Samsung ARM7-core microcontroller S3C44B0X, and the hardware design adding the GPRS engine MC35i produced by Siemens and RS485 interface to the minimum system. According to dial-up procedure, describes how to design the MC35i dial-up program. Here introduces some important subsets of AT command sets, and also describes how to use them to dial up MC35i; analyzes the principle of the point-to-point protocol, and also demonstrates how to establish the wireless link to GPRS by practical example.