The paper sets out to investigate the performance of innovation network from the perspectives of relationship capital, coupling mechanism and innovative capacity of regional innovation network nodes. With High-tech Development Zone and University Technology Park as the objects of investigation, the paper finally comes to the conclusion that the accumulation of previous cooperation experience and macro and microcosmic relationship capital of regional innovation network nodes is conducive to the formation of a sound coupling mechanism among nodes and the enhancement of relationship, interaction and coordination among nodes will further upgrade the innovation performance of regional innovation network.