In this paper we propose a portable and compact system for real-time monitoring/assessing of individuals fatigue under active conditions based on measurements of eyes. Real-time monitoring of fatigue - cognitive, physiological, and physical - can help supervisors and commanders to prudently assign tasks so as to prevent human errors and causalities. The proposed system utilizes a very small camera mounted on the frame of eye glasses. Five parameters of human eyes are measured and their significant variations are reported to a monitoring center using the hardware installed in the helmet. The experimental results and case studies showed that this system can be reliably employed for move-free monitoring individual fatigue.