INTERLIFE is an EU 1ST e-TEN project aiming in enhancing healthcare services by introducing new means for quality health care management via telemedicine services, and by improving the patients' and citizens' quality of life. INTERLIFE, based largely on the results of the citizen health system (CHS) EU 1ST, is a technological and medical knowledge management and processing infrastructure able to support among others patients suffering from chronic cardiac diseases such as congestive heart failure (CHF). The preliminary results of INTERLIFE CHF pilot presented here show the possibilities of this service in the treatment of chronic diseases, such as CHF, both in terms of hospitalization reduction and towards improvement of vital signs.