Conditioning agents are usually used to improve the collection efficiency of electrostatic precipitators by causing a reduction in the resistivity of the fly ash. However, certain conditioning agents may have other effects including changing the electrical breakdown strength of the flue gas, space charge enhancement of the collecting field, increasing the mean particle size, changing the adhesion and cohesion properties of the ash, and changing the acid dew point of the flue gas. These mechanisms are reviewed and related to results reported in the literature for ammonia and triethylamine, two conditioning agents which appear able to affect one or more of the mechanisms mentioned above, in addition to the resistivity.