HTTP (Hyper Text Transfer Protocol) and TCP (Transmission Control Protocol) are usually used to retrieve objects in the Internet. Stream Control Transmission Protocol (SCTP) has attractive multi-streaming feature, which allows for independent delivery among streams, thus can avoid the head-of-line blocking experienced by TCP and reduce the mean response time of users. We present an analytical model and algorithm to estimate the mean response time for HTTP over SCTP and compare with that of HTTP over TCP in the wireless environment. We validate the accuracy of our model using experiments. It is shown that mean response time for HTTP over SCTP is less than that for HTTP over TCP by 20% on average.