The Veterinary Journal

Items from 1 to 20 out of 21 results

article

Effect of Parachlamydia acanthamoebae on pulmonary function parameters in a bovine respiratory model

M. Lohr, A. Prohl, C. Ostermann, R. Diller, more

The Veterinary Journal > 2016 > 213 > C > 9-15

The aim of this study was to evaluate pulmonary dysfunction induced by experimental infection with Parachlamydia acanthamoebae in calves. Intrabronchial inoculation with P. acanthamoebae was performed in 31 calves aged 2–3 months old at two different challenge doses of 10⁸ and 10¹⁰ inclusion-forming units (IFU) per animal. Control animals received heat inactivated bacteria. The effects on pulmonary...

article

Designing a field trial of an equine grass sickness vaccine: A questionnaire-based feasibility study

Joanne L. Ireland, Bruce C. McGorum, Christopher J. Proudman, J. Richard Newton

The Veterinary Journal > 2016 > 213 > C > 64-71

Without an experimental model of equine grass sickness (EGS), a randomised controlled field trial (RCT) represents the only method of evaluating the efficacy of Clostridium botulinum type C vaccination in preventing naturally occurring disease. Clinical trial feasibility is an important aspect of preliminary work undertaken prior to initiating RCTs, estimating parameters that are important for study...

article

Engineering of a live Salmonella enterica serovar Choleraesuis negative-marker strain that allows serological differentiation between immunised and infected animals

Aldara Herrero-Gil, Javier Carrión, Jose A. Orden, Ricardo de la Fuente, more

The Veterinary Journal > 2016 > 213 > C > 53-58

The usefulness of Salmonella vaccine vehicles is limited by the fact that control programmes relying on Salmonella bacteriology and serology cannot differentiate infected animals from vaccinated ones, an ability referred to as DIVA (differentiating infected from vaccinated animals). As a first step towards Salmonella-based DIVA vaccines, the ompA gene was deleted in live attenuated ΔphoP and ΔrpoS...

article

New DIVA vaccine for pigs

Trevor M Ellis

The Veterinary Journal > 2016 > 213 > C > 16-17

article

Randomised clinical trial on the effect of a single oral administration of l-tryptophan, at three dose rates, on reaction speed, plasma concentration and haemolysis in horses

Glenys K. Noble, Xiuhua Li, Dagong Zhang, Martin N. Sillence

The Veterinary Journal > 2016 > 213 > C > 84-86

Tryptophan (TRP) is marketed as a calmative for horses despite reservations about its efficacy. The aim of this study was to measure the effect of oral TRP administration on the reaction speed of horses. Sixty mature horses were used in a two stage randomised, blind, cross-over study, receiving a placebo and an oral dose of TRP (30, 60 or 120 mg/kg body weight), before undergoing a reaction speed...

article

Equine aortic regurgitation: The search for objective repeatable and reproducible indicators of severity

John A Keen

The Veterinary Journal > 2016 > 213 > C > 91-92

article

Insulin dysregulation and obesity: You are what you eat

Andy E. Durham

The Veterinary Journal > 2016 > 213 > C > 90

article

The holy grail of cartilage defect repair: Crossing species and disciplinary boundaries

Maarten Oosterlinck

The Veterinary Journal > 2016 > 213 > C > 24-25

article

The effect of topical lidocaine on muscle artefacts in awake canine electroencephalogram recordings

Jordan Ward, Fiona James, Gabrielle Monteith

The Veterinary Journal > 2016 > 213 > C > 6-8

Muscle artefacts in electroencephalogram recording data interfere with diagnostic accuracy. Lidocaine may reduce these artefacts. The objective of this study was to determine the effect of topical lidocaine on muscle artefacts in unanesthetized canine electroencephalogram (EEG) recording data. Topical 4% lidocaine was applied to each electrode site for six treated dogs prior to subdermal wire electrode...

article

Repeated measurements of blood lactate concentration as a prognostic marker in horses with acute colitis evaluated with classification and regression trees (CART) and random forest analysis

M.B. Petersen, A. Tolver, L. Husted, T.H. Tølbøll, more

The Veterinary Journal > 2016 > 213 > C > 18-23

The objective of this study was to investigate the prognostic value of single and repeated measurements of blood l-lactate (Lac) and ionised calcium (iCa) concentrations, packed cell volume (PCV) and plasma total protein (TP) concentration in horses with acute colitis. A total of 66 adult horses admitted with acute colitis (<24 h) to a referral hospital in the 2002–2011 period were included. The...

article

First impressions: Cytology from the surface of the brain

Mark Lowrie

The Veterinary Journal > 2016 > 213 > C > 46-47

article

Pathological and immunological features of canine necrotising meningoencephalitis and granulomatous meningoencephalitis

Kazuyuki Uchida, Eunsil Park, Masaya Tsuboi, James K. Chambers, more

The Veterinary Journal > 2016 > 213 > C > 72-77

Necrotising meningoencephalitis (NME) and granulomatous meningoencephalitis (GME) are idiopathic inflammatory diseases of the canine central nervous system (CNS). Typical NME occurs predominantly in small breeds of dogs, such as Pug, Maltese and Yorkshire terriers. Although there is no specific breed predisposition to GME, toy and terrier breeds appear to be overrepresented. Recent molecular investigations...

article

Natural history of canine paroxysmal movement disorders in Labrador retrievers and Jack Russell terriers

Mark Lowrie, Laurent Garosi

The Veterinary Journal > 2016 > 213 > C > 33-37

Delineation of the typical disease progression in canine paroxysmal dyskinesia (PD) may assist in evaluating therapeutic agents during clinical trials. Our objective was to establish the natural disease course in a group of dogs diagnosed with PD that received no medication. Fifty-nine dogs (36 Labradors, 23 JRTs) with clinically confirmed PD and a follow-up of ≥3 years were retrospectively reviewed...

article

Effect of a constant rate infusion of cytosine arabinoside on mortality in dogs with meningoencephalitis of unknown origin

M. Lowrie, S. Thomson, P. Smith, L. Garosi

The Veterinary Journal > 2016 > 213 > C > 1-5

Administration of cytosine arabinoside (CA) by continuous rate infusion (CRI) has pharmacokinetic and pharmacodynamic advantages over traditional intermittent dosing. Whether these advantages translate into clinical efficacy remains unknown. The aim of this study was to assess the efficacy and safety of CRI of CA in dogs with meningoencephalitis of unknown origin (MUO) and to compare outcomes with...

article

Veterinary oncology: Biology, big data and precision medicine

Lisa Y. Pang, David J. Argyle

The Veterinary Journal > 2016 > 213 > C > 38-45

Despite significant advances in both the understanding and the treatment of cancer, the disease remains one of high mortality and morbidity causes in all species. Increases in survival times in human cancer have increased significantly in the past 25 years but most of these increases have been through small incremental changes. For some cancers, e.g. pancreatic cancer, survival times have not increased...

article

Herd-level risk factors for bovine tuberculosis and adoption of related biosecurity measures in Northern Ireland: A case-control study

M.J.H. O'Hagan, D.I. Matthews, C. Laird, S.W.J. McDowell

The Veterinary Journal > 2016 > 213 > C > 26-32

Bovine tuberculosis (bTB) is a zoonotic disease which is endemic in Northern Ireland. As it has proven difficult to eradicate this disease, partly due to a wildlife reservoir being present in the European badger (Meles meles), a case-control study was conducted in a high incidence area in 2010–2011. The aim was to identify risk factors for bTB breakdown relating to cattle and badgers, and to assess...

article

The effect of imepitoin, a recently developed antiepileptic drug, on thyroid parameters and fat metabolism in healthy Beagle dogs

K. Bossens, S. Daminet, L. Duchateau, M. Rick, more

The Veterinary Journal > 2016 > 213 > C > 48-52

Since early 2013, imepitoin has been used in most European countries for the management of recurrent single generalised epileptic seizures in dogs with idiopathic epilepsy. It has been reported that imepitoin is as effective as phenobarbital (PB) in controlling seizures in dogs with newly diagnosed idiopathic epilepsy and it has a clinically superior safety profile. As the use of imepitoin gains popularity,...

article

Assessment of temporal association of relapse of canine multicentric lymphoma with components of the CHOP protocol: Is cyclophosphamide the weakest link?

Shang-Lin Wang, Jih-Jong Lee, Albert Taiching Liao

The Veterinary Journal > 2016 > 213 > C > 87-89

Combination chemotherapy, using cyclophosphamide, hydroxydaunorubicin, vincristine and prednisolone (CHOP), is the most commonly used treatment for canine lymphoma. Most affected dogs respond during the initial stages of chemotherapy, but many relapse. The aim of this study was to evaluate the relationship between the use of specific chemotherapy drugs and clinical relapse, using the modified Madison-Wisconsin,...

article

Comparison of in vivo confocal endomicroscopy with other diagnostic modalities to detect intracellular helicobacters

M. Sharman, B. Bacci, K. Simpson, C. Mansfield

The Veterinary Journal > 2016 > 213 > C > 78-83

Intracellular colonisation may serve as a protected niche where Helicobacter spp. organisms evade effective treatment. In dogs, non-Helicobacter pylori-helicobacters are frequently intracellular. Confocal endomicroscopy allows in vivo gastrointestinal imaging and has aided real-time identification of Helicobacter pylori and other intracellular and mucosally associated bacteria. The objectives of this...

article

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The Veterinary Journal > 2016 > 213 > C > i

Volume:
213
Year:
2016

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CANINE (6)
TREATMENT (2)
ANTIEPILEPTIC DRUG (1)
ATTENUATED DIVA STRAIN (1)
BEHAVIOUR (1)
BIG DATA (1)
BIOSECURITY (1)
BLOOD GAS ANALYSIS (1)
BOVINE TUBERCULOSIS (1)
BRONCHOPNEUMONIA (1)
CANCER (1)
CASE-CONTROL STUDY (1)
CHEMOTHERAPY (1)
CHLAMYDIA-LIKE ORGANISM (1)
CHOLESTEROL (1)
CLASSIFICATION AND REGRESSION TREES (CART) (1)
CLINICAL TRIAL (1)
COLITIS (1)
CYCLOPHOSPHAMIDE (1)
CYTOSINE ARABINOSIDE (1)
DOG (1)
DYSKINESIA (1)
ELECTROENCEPHALOGRAM (1)
ENDOSCOPY (1)
EQUINE (1)
EQUINE GRASS SICKNESS (1)
FLUORESCENCE IN SITU HYBRIDISATION (1)
GAIT (1)
GASTRIC (1)
GRANULOMATOUS MENINGOENCEPHALITIS (1)
HISTOPATHOLOGY (1)
HORSES (1)
IMMUNE RESPONSE (1)
LACTATE (1)
LARGE ANIMAL MODEL (1)
LIPOSOMAL LIDOCAINE (1)
LOCOMOTION (1)
LYMPHOMA (1)
MENINGOENCEPHALITIS OF UNKNOWN ORIGIN (1)
MUSCLE ARTEFACTS (1)
MYCOBACTERIUM BOVIS (1)
NECROTISING LEUCOENCEPHALITIS (1)
NECROTISING MENINGOENCEPHALITIS (1)
OMPA (1)
PARALYSIS (1)
PCR (1)
PRECISION MEDICINE (1)
PROGNOSIS (1)
PROGRESSION (1)
PULMONARY FUNCTION (1)
RANDOMISED CLINICAL TRIAL (1)
RANDOMISED CONTROLLED FIELD TRIAL (RCT) (1)
REACTION SPEED (1)
RELAPSE (1)
RISK FACTORS (1)
SALMONELLA CHOLERAESUIS (1)
SEIZURE (1)
SPINAL CORD INJURY (1)
SUBDERMAL WIRE ELECTRODES (1)
THYROID (1)
TRIGLYCERIDES (1)
TRYPTOPHAN (1)
VACCINE (1)
VACCINE DELIVERY VECTOR (1)
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INFONA - science communication portal

The Veterinary Journal

Effect of Parachlamydia acanthamoebae on pulmonary function parameters in a bovine respiratory model

Designing a field trial of an equine grass sickness vaccine: A questionnaire-based feasibility study

Engineering of a live Salmonella enterica serovar Choleraesuis negative-marker strain that allows serological differentiation between immunised and infected animals

New DIVA vaccine for pigs

Randomised clinical trial on the effect of a single oral administration of l-tryptophan, at three dose rates, on reaction speed, plasma concentration and haemolysis in horses

Equine aortic regurgitation: The search for objective repeatable and reproducible indicators of severity

Insulin dysregulation and obesity: You are what you eat

The holy grail of cartilage defect repair: Crossing species and disciplinary boundaries

The effect of topical lidocaine on muscle artefacts in awake canine electroencephalogram recordings

Repeated measurements of blood lactate concentration as a prognostic marker in horses with acute colitis evaluated with classification and regression trees (CART) and random forest analysis

First impressions: Cytology from the surface of the brain

Pathological and immunological features of canine necrotising meningoencephalitis and granulomatous meningoencephalitis

Natural history of canine paroxysmal movement disorders in Labrador retrievers and Jack Russell terriers

Effect of a constant rate infusion of cytosine arabinoside on mortality in dogs with meningoencephalitis of unknown origin

Veterinary oncology: Biology, big data and precision medicine

Herd-level risk factors for bovine tuberculosis and adoption of related biosecurity measures in Northern Ireland: A case-control study

The effect of imepitoin, a recently developed antiepileptic drug, on thyroid parameters and fat metabolism in healthy Beagle dogs

Assessment of temporal association of relapse of canine multicentric lymphoma with components of the CHOP protocol: Is cyclophosphamide the weakest link?

Comparison of in vivo confocal endomicroscopy with other diagnostic modalities to detect intracellular helicobacters

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