The NMR pulse method has been used to study the biophysical features of the water exchange of plant tissues on exposure to modifiers of the structural state of the protein of the cytoskeleton. From the changes in the effective self-diffusion coefficient of water and the spin-spin relaxation times it is concluded that the water permeability of plant cell membranes increases, which may be a consequence of the developed membranotropic effect by the inhibitor of tubulin proteins, colchicine, and the antimitotic agent, vinblastine.