Deficit schizophrenia (DS) with persistent, primary negative symptoms has a confirmed neuroanatomical background, similarly to structures involved in the process of taste. DS may be regarded as a subtype of schizophrenia caused by neurodevelopmental disorders, with probable link to specific genetic traits which are responsible for the formation of synapses and neuroplasticity. The process eventually leads to symptoms of the illness and physiologic disorders affecting the perception of taste.The study of threshold of taste perception (TTP) was part of the search for the helpful marker to identify DS patients.Taste evaluation was supposed to determine differences in TTP-MSG between DS and NDS.Eighty-two patients with DS and 72 patients with NDS (nondeficit schizophrenia), somatically healthy and without acute psychotic symptoms were subjected to TTP-MSG: seven triplets (water, water, 0,0001%-1% MSG) were applied. Demographic and psychometric data were analyzed.An analysis of TTP-MSG did not disclose differences between DS and NDS. Most patients in both groups correctly detected the taste starting from 0,1% MSG. No differences in other collected data were found between DS and NDS.Physiologic studies of TTP-MSG should not be the base for differentiation between DS and NDS groups of patients. This work was supported by grant MNiSW no N N402 456738.