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Malfunctions of the basal ganglia cause movement disorders, such as Parkinson's disease and dystonia. Several models have been proposed to explain the pathophysiology of these disorders: (1) firing rate model: activity imbalance between the direct and indirect pathways changes the mean firing rates of the output nuclei of the basal ganglia and induces hypokinetic or hyperkinetic movement disorders;...
A conference was organized by the Hungarian Academy of Sciences in honour of Professor Laszlo Zaborszky, to recapitulate the progress and identify principal directions for future studies of circuit architecture and connections in forebrain systems. Neuroscientists gathered in Tihany to present and debate latest discoveries of the organizational rules and functions of local and long-range basal forebrain...
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