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The objective of the work was to prepare chitosan–Ca–alginate microparticles that can effectively deliver 5-ASA to the colon after peroral administration. For these requirements, a spray-drying technique was applied to 5-ASA/sodium alginate aqueous solution to obtain spherical particles having a mean diameter less than 10μm. The microparticles formed were cross-linked and coated into solution of CaCl...
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