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The objective of this work was to evaluate the potential of using (SBE) 7m -β-CD and HP-β-CD as enabling excipients to improve on the current melphalan injectable formulation. Melphalan is an anti-neoplastic agent formulated for parenteral use as a sterile, non-pyrogenic, freeze-dried powder. It is marketed by Glaxo-Wellcome as ALKERAN ( R) for Injection (Alkeran). A major concern...
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