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This study investigated the effects of mulberry leaf extract (MLE) and mulberry leaf polyphenol extract (MLPE) on lipid accumulation in 3T3-L1 cells and obesity in mice fed a high-fat diet (HFD). MLPE was extracted from mulberry leaves using ethanol, and those polyphenolic compounds that can be analysed by HPLC. Both MLE and MLPE efficiently suppressed the expression of SREBP-1c and PPAR-γ proteins...
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