To compare the early and late outcomes of using two different stent types, angiographic follow up was done 3 months (3 M) after Wiktor (W) (86 patients with 105 lesions) and Palmaz-Schatz (PS) (561 patients with 631 lesions) stent implantation. Furthermore, the coronary arteries of the patients who died between 2 days and 3 M after W (7 lesions) and PS (10 lesions) stent implantation were investigated histopathologically and immunohistochemically.Macroscopic examination of the specimens from the patients who died after W stent implantation revealed that the coil configuration allowed the deployed stent conform with the natural course of the tortuous coronary arteries and ensure excellent perfusion through side branches whose origins were covered by the stent. However, although W stent struts locally depressed the arterial wall, causing thinning and stretching of the atherosclerotic plaque-free wall segment, some of the struts frequently could not attach to the surface of the atheroma due to their wear after 3 M. In these segments, there were a lot of fibrin deposits around the stent struts, especially at the gap between the struts and the atheroma surface. In contrast, in PS stenting, the whole struts appeared to deeply sink into the atheroma, and there was a small amount of fibrin deposits and infiltration of blood elements around the stent struts. Furthermore, the struts were embedded in the arterial wall and completely covered by a neointimal layer after 1.5 months.Thus, this study provides a pathologic support for the angiographic data suggesting that the radial force of W stent is inferior to that of PS stent, and it may lead a high incidence of subacute stent thrombosis and late restenosis.