A conventional nonelectrolyte self-associated solution model, which has led to successful descriptive equations for excess molar enthalpies and excess molar Gibbs free energies, is extended to systems containing an inert solute dissolved in binary hydrocarbon + alcohol solvent mixtures. An expression is derived for predicting the solubility of crystalline solutes from a prior knowledge of the solubility in the two pure solvents. Applications and limitations of the newly derived equation were assessed using published solubility data for anthracene in 30 different binary solvent systems containing 1-propanol, 2-propanol, 1-butanol, 2-butanol or 1-octanol. The derived expression predicted the observed values to within an overall average absolute deviation of approximately 5.7% using zero adjustable curve-fit parameters. Mobile order theory, in comparison, provides comparable predictions, with deviations between predicted and experimental values also being on the order of approximately 5.7%.