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Ultrasound (US) is one of the most frequently used imaging methods in the clinic. The broad spectrum of its applications can be increased by the use of gas-filled microbubbles (MB) as ultrasound contrast agents (UCA). In recent years, also nanoscale UCA like nanobubbles (NB), echogenic liposomes (ELIP) and nanodroplets have been developed, which in contrast to MB, are able to extravasate from the...
In nuclear medicine, a theranostic probe describes a substance that combines diagnostic and therapeutic capabilities by radiolabeling it with different radionuclides. Next to a brief description of the different emitters (α, β+, β−, γ) used for imaging and/or therapy, the aim of this review is to summarize the most commonly used theranostic probes in nuclear medicine. Another goal is to give an idea...
Despite the significant advancement achieved in understanding the molecular mechanisms responsible for cancer transformation and aberrant proliferation, leading to novel targeted cancer therapies, significant effort is still needed to “personalize” cancer treatment. Molecular imaging is an emerging field that has shown the ability to characterize in vivo the molecular pathways present at the cancer...
Atherosclerotic events are usually acute and often strike otherwise asymptomatic patients. Although multiple clinical risk factors have been associated with atherosclerosis, as of yet no further individual prediction can be made as to who will suffer from its consequences based on biomarker analysis or traditional imaging methods like CT, MRI or angiography.Previously, non-invasive imaging with 18...
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