Coptis teeta Wall. belongs to the family of Rununculacaeae, which is 20–50cm in height. The rhizome is 5–6-cm long, is brownish yellow, is densely covered with numerous nodes and often with rootlets. Its interior is yellow–orange; in the transverse section, the central pith is deeper in color. It is more common in the hilly areas, especially that of the Himalayan region. It is more commonly found in Bhutan, Nepal and China. In India it is found in Assam (Mishmi Mountains), Arunachal Pradesh, and Sikkim. It is used for applying in inflammatory eye diseases, decrease vision, cataract, skin-related problems, indigestion, constipation, jaundice, fever especially in malaria, gonorrhea, and urine disorders. The root is a pungent, very bitter, cooling herb that contains several compounds that are effective in inhibiting various bacteria and they are a safe and effective treatment for many ailments, such as some forms of dysentery, which are caused by bacteria. The root contains 8–8.5% of berberine, which is considered as the active ingredients of the plant. It also contains alkaloids like coptine or coptina. It also contains fixed oil, albumin, coloring matter, lignin, extractive, and sugar. It has been thought worthwhile to undertake the physico-chemical standardization of Mamira (Coptis teeta Wall.) for their identity, purity, and strength.Thus it is used widely in ocular ailments in the Unani system of medicine as a drug of choice and has proved beneficial and safe.