Four complexes: [Bu 2 (L 1 )SnOSn(L 1 )Bu 2 ] 2 (1), [Bu 2 (L 2 )SnOSn(L 2 )Bu 2 ] 2 (2), [Bu 2 (L 3 )SnOSn(L 3 )Bu 2 ] 2 (3), and [Bu 2 (L 4 )SnOSn(L 4 )Bu 2 ] 2 (4), (HL 1 =2-(4-methylbenzoyl)benzoic acid, HL 2 =2-(2,4-diethylbenzoyl)benzoic acid, HL 3 =2-(4-chlorobenzoyl)benzoic acid, HL 4 =2-(4-isopropylbenzoyl)benzoic acid) have been prepared and structurally characterized by means of elemental analysis and vibrational, 1 H NMR and FT-IR spectroscopies. The crystal structures of all complexes have been determined by X-ray crystallography. Three distannoxane rings are present to the dimeric tetraorganodistannoxane of planar ladder arrangement. Each structure is centro-symmetric and features a central rhombus Sn 2 O 2 unit with two additional tin atoms linked at the O atoms. Complex 1 exhibited good antibacterial and antitumor activities and have a potential to be used as drugs.