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Portulacerebroside A (PCA) is a novel cerebroside compound isolated from Portulaca oleracea L. The present results showed that PCA significantly inhibited cell viability time- and dose-dependently, elicited chromatin aggregation and fragmented nuclei, and enhanced the percentage of apoptotic cells. Furthermore PCA remarkably increased the protein phosphorylation of p38 MAPK and JNK, disrupted mitochondrial...
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