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The loss of dopamine in idiopathic or animal models of Parkinson’s disease induces synchronized low-frequency oscillatory burst-firing in subthalamic nucleus neurones. We sought to establish whether these firing patterns observed in vivo were preserved in slices taken from dopamine-depleted animals, thus establishing a role for the isolated subthalamic–globus pallidus complex in generating the pathological...
Dopamine (DA) is produced in numerous brain areas and influences a wide variety of social behaviors, but very few data are available to establish the socially-relevant response properties of most DA populations, which comprise eight cell groups numbered A8–A15. Anatomically, these DA populations are evolutionarily conserved, and all have been identified in both birds and mammals. We now report the...
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