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The contribution of intracortical inhibition to orientation tuning in the cat striate cortex (area 17) was studied by responses to flashing light bars of different orientations and lengths in 68 single-units before and during microiontophoretical application of bicuculline, a GABA A antagonist, A three-fold increase in the background activity (13.3±1.3 vs 4.4±0.5imp/s) and 4.4-fold increase...
Orientation tuning of some neurons in cat visual cortex (area 17) revealed successive shifts of the preferred orientation and widening of tuning in time during the first 150ms after onset of a flashing light bar. The mechanisms of these dynamics and the possible role of intracortical inhibition are still under discussion. In this study we analysed the dynamics using the time slice method before and...
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